Process Plus provided all engineering and architectural services for the renovation of an existing encapsulation suite area into an expanded tablet production suite with controlled airlock entry. The transformation was designed for the installation of a special two part high speed tablet press. Product driven facility requirements included the need for the manufacturing area to be provided with a special 25% relative humidity operating environment.
Process Plus completed the design for approximately 94,000 square foot retrofit of an existing pharmaceutical manufacturing facility and warehouse area for the micronization, conditioning, milling, blending, encapsulation, blister packaging, cartoning and palletizing of a lactose/level 3 potent compound product. The production areas were designed as pharmaceutically classified areas per FDA and EMEA requirements.
Process Plus worked closely with the owner and a material handling equipment manufacturer to develop a fully automated system for the exchange of finished goods from a special plastic pallet to a wooden pallet with the plastic pallet being cleaned and returned to production. An additional requirement of the system was the separation of DEA controlled products from non-controlled products after pallet exchange. Process Plus provided the Engineering, Architectural and Installation coordination services for the above system.
This project was a build-out of a multi-product manufacturing facility in Ohio. This project included installation of an aseptic vial filling line for sterile injectable products. This included the facilities and HVAC systems necessary for personnel and material access control as well as sterile processing. The addition of a shipping warehouse and conditioned storage facilities for finished products was provided. This project was a continuation of a program that included multiple process rooms for manufacturing the sterile compounds.
Process Plus provided all Engineering and Architectural services to complete the transformation of an existing area for the consolidation and upgrade of tablet coating processes, printing and inspection. Included as part of the project were upgrades to material handling, new air handling systems, and full qualification of all installed systems. Multiple size coating systems, handling solvent based, water based, and sugar coatings were to be incorporated into the coating area.
Process Plus provided architectural, structural, mechanical, and electrical design for the renovation and expansion of an existing Pharmaceutical facility. The facility was expanded to provide new process and production capabilities. Approximately 12,000 square feet of new cGMP area was constructed while the existing facility operations were maintained.
This project was a build out of a multi-product manufacturing suite in Ohio. This project included installation of an aseptic vial filling line for sterile injectable products.